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Structure of 438613-29-7
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6-Bromo-3-chlorobenzo[b]thiophene-2-carboxylic acid features a fused heterocyclic core with strategically positioned halogen substituents enabling direct functionalization in cross-coupling reactions. The carboxylic acid group provides a handle for derivatization, while the electron-deficient thiophene ring enhances reactivity in transition-metal-catalyzed transformations. This scaffold offers high stability under standard conditions and is well-suited for pharmaceutical and agrochemical synthesis.
6-Bromo-3-chlorobenzo[b]thiophene-2-carboxylic acid serves as a versatile building block for the synthesis of biologically relevant heterocycles and pharmaceutical intermediates. Its dual halogenation pattern enables selective cross-coupling reactions, while the carboxylic acid functionality facilitates derivatization via amide, ester, or acyl transfer protocols. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: