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CS-W001157 4
Total: USD 88.00

3-Bromo-5-(trifluoromethyl)pyridine

  • CAS No. 436799-33-6

  • Cat. No. CS-W007687
  • Purity≥98%
  • MDL No.MFCD04972700

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-(trifluoromethyl)pyridine|CS-W007687

Structure of 436799-33-6

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General Information

  • CAS No. 436799-33-6
  • Cat. No. CS-W007687
  • Purity ≥98%
  • MDL No. MFCD04972700
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrF₃N
  • Molecular Weight 225.99
  • Synonym(s) None
  • SMILES BrC1=CN=CC(C(F)(F)F)=C1

Description

3-Bromo-5-(trifluoromethyl)pyridine features a trifluoromethyl group at the 5-position and a bromine substituent at the 3-position of the pyridine ring. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient construction of complex pharmaceutical intermediates and functional materials under standard conditions.

Synthesis

  • Route1

    References

    • Xue, Chu-Biao; Zheng, Changsheng; Feng, Hao; Xia, Michael; Glenn, Joseph; Cao, Ganfeng.; Metcalf, Brian W. Patent: US2006/4018 A1, 2006 ; Location in patent: Page/Page column 14; 36 ; US 20060004018 A1
  • Route2

    References

    • Cottet, Fabrice; Schlosser, Manfred European Journal of Organic Chemistry, 2002 , # 2 p. 327 - 330
  • Route3

    References

    • Cottet, Fabrice; Schlosser, Manfred European Journal of Organic Chemistry, 2002 , # 2 p. 327 - 330

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H300-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.8629
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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