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CS-W001157 4
Total: USD 88.00

Ethyl 6-aminonicotinate

  • CAS No. 39658-41-8

  • Cat. No. CS-W019557
  • Purity≥97%
  • MDL No.MFCD04972544

*For research and further manufacturing use only, not for direct human use.

Ethyl 6-aminonicotinate|CS-W019557

Structure of 39658-41-8

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General Information

  • CAS No. 39658-41-8
  • Cat. No. CS-W019557
  • Purity ≥97%
  • MDL No. MFCD04972544
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂
  • Molecular Weight 166.18
  • Synonym(s) ethyl 6-aminopyridine-3-carboxylate
  • SMILES O=C(OCC)C1=CN=C(N)C=C1

Description

Ethyl 6-aminonicotinate features a pyridine core bearing both electron-rich amine and ester functionalities, enabling direct incorporation into pharmaceutical scaffolds. This bench-stable derivative delivers enhanced solubility in polar organic solvents and serves as a key intermediate for targeted synthesis of bioactive heterocycles.

Application

Ethyl 6-aminonicotinate serves as a versatile building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and pharmaceutical intermediates. The ortho-amino and ester functionalities offer complementary reactivity for diverse transformations, including amidation, cyclization, and transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard purification methods make it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   65.21
  • LogP   0.8405
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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