Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

N-Boc-5-Hydroxyindole

  • CAS No. 434958-85-7

  • Cat. No. CS-W019295
  • Molecule weight233.26
  • Purity≥97%
  • MDL No.MFCD08272246

*For research and further manufacturing use only, not for direct human use.

N-Boc-5-Hydroxyindole|CS-W019295

Structure of 434958-85-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 434958-85-7
  • Cat. No. CS-W019295
  • Purity ≥97%
  • MDL No. MFCD08272246
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₅NO₃
  • Molecular Weight 233.26
  • Synonym(s) tert-butyl 5-hydroxyindole-1-carboxylate
  • SMILES C(=O)(OC(C)(C)C)[N]2C1=CC=C(C=C1C=C2)O

Description

N-Boc-5-Hydroxyindole delivers a protected indole scaffold with a strategically positioned hydroxyl group, enabling direct incorporation into complex alkaloid syntheses. This bench-stable derivative simplifies handling of the reactive phenolic functionality while maintaining compatibility with standard deprotection and coupling protocols.

Application

N-Boc-5-Hydroxyindole serves as a versatile building block for the synthesis of indole-based pharmaceuticals and bioactive heterocycles. The Boc group provides excellent stability and orthogonal protection, enabling selective deprotection under mild acidic conditions. The phenolic hydroxyl group allows for direct functionalization or derivatization, while the indole core supports standard coupling reactions, making this intermediate highly valuable in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • tert-Butyl 5-(benzyloxy)-1H-indole-1-carboxylate|CS-0154784
      170147-29-2
    • ~95%
    • In-stock
      N-Boc-5-Hydroxyindole|CS-W019295
      434958-85-7

    References

    • WO2007/76034 A2, ; Page/Page column 127 ;
  • Route2

    References

    • EP2108642 A1, ; Page/Page column 87 ;
  • Route3

    References

    • Angewandte Chemie - International Edition, , vol. 51, # 33 p. 8304 - 8308

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.46
  • LogP   3.1301
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • N-Boc-5-Hydroxyindole sigmaN-Boc-5-Hydroxyindole manufacturerN-Boc-5-Hydroxyindole priceN-Boc-5-Hydroxyindole structureN-Boc-5-Hydroxyindole SDSbuy N-Boc-5-HydroxyindoleN-Boc-5-Hydroxyindole supplierN-Boc-5-Hydroxyindole usesN-Boc-5-Hydroxyindole molecular weightprice of N-Boc-5-HydroxyindoleN-Boc-5-Hydroxyindole chemical name formula of N-Boc-5-Hydroxyindole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label