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CS-W001157 4
Total: USD 88.00

5-Bromo-2-nitropyridin-3-amine

  • CAS No. 433226-05-2

  • Cat. No. CS-0042076
  • Purity≥96%
  • MDL No.MFCD11040269

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-nitropyridin-3-amine|CS-0042076

Structure of 433226-05-2

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General Information

  • CAS No. 433226-05-2
  • Cat. No. CS-0042076
  • Purity ≥96%
  • MDL No. MFCD11040269
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄BrN₃O₂
  • Molecular Weight 218.01
  • Synonym(s) 3-AMINO-5-BROMO-2-NITROPYRIDINE
  • SMILES NC1=CC(Br)=CN=C1[N+]([O-])=O

Synthesis

  • Route1
    • Ethyl (5-bromo-2-nitropyridin-3-yl)carbamate|CS-0626703
      152684-25-8
    • ~93%
    • In-stock
      5-Bromo-2-nitropyridin-3-amine|CS-0042076
      433226-05-2

    References

    • van Duzer, John H.; Mazitschek, Ralph Patent: US2014/128391 A1, 2014 ; Location in patent: Paragraph 0226; 0231; 0232 ;
  • Route2

    References

    • AVEXA LIMITED; SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY (SIOC); RHODES, David, Ian; DEADMAN, John, Joseph; LE, Giang, Thanh; VAN DE GRAFF, Nicholas, Andrew; LONG, Lu; XINMING, Li; XIAO, Feng; CHANGJIANG, Yu Patent: WO2012/6680 A1, 2012 ; Location in patent: Page/Page column 76 ;
  • Route3
    • Ethyl (5-bromopyridin-3-yl)carbamate|CS-0626702
      152684-24-7
    • ~%
    • In-stock
      5-Bromo-2-nitropyridin-3-amine|CS-0042076
      433226-05-2

    References

    • Hasegawa, Masaichi; Nishigaki, Naohiko; Washio, Yoshiaki; Kano, Kazuya; Harris, Philip A.; Sato, Hideyuki; Mori, Ichiro; West, Rob I.; Shibahara, Megumi; Toyoda, Hiroko; Wang, Liping; Nolte, Robert T.; Veal, James M.; Cheung, Mui Journal of Medicinal Chemistry, 2007 , vol. 50, # 18 p. 4453 - 4470

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   82.05
  • LogP   1.3345
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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