4,6-Dichloro-5-methylpyrimidine

Name: 4,6-Dichloro-5-methylpyrimidine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 4316-97-6
Cat. No. CS-W002807
Purity≥98%
MDL No.MFCD01646112

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloro-5-methylpyrimidine|CS-W002807

Structure of 4316-97-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 4316-97-6
Cat. No. CS-W002807
Purity ≥98%
MDL No. MFCD01646112
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄Cl₂N₂
Molecular Weight 163.01
Synonym(s) Pyrimidine, 4,6-dichloro-5-methy; 4,6-Dichloro-5-methylpyrimidine
SMILES Clc1ncnc(c1C)Cl

Description

It is employed as an electrophoresis tracking dye and also finds its uses as an industrial dye, a laboratory acid-base indicator and a biological stain to detect proteins and nucleic acids (absorbance at 610 nm), particularly when staining living tissues. In gel electrophoresis it can be used as a color marker and as a biological stain it can be used to stain proteins and nucleic acids. Bromophenol blue is an intermediate and is used as an acid-based indicator in the pH range of 3-4.6 where the color changes from yellow to blue.

Application

4,6-Dichloro-5-methylpyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds through palladium-catalyzed cross-coupling reactions. Its dual chloro groups at C4 and C6 offer orthogonal reactivity for sequential functionalization, while the methyl substituent at C5 enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard reaction conditions, facilitating straightforward purification and scalability in multi-step syntheses.

Synthesis

Route1
- In-stock
  
  18337-63-8
- ~89%
- In-stock
  
  4316-97-6
References
- Gharbaoui, Tawfik; Fritch, John R.; Krishnan, Ashwin M.; Throop, Beverly Wolgast; Kato, Naomi S. Patent: US2006/155129 A1, 2006 ; Location in patent: Page/Page column 14 ; US 20060155129 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 3261
Class : 8	Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 25.78
LogP 2.09182
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

4,6-Dichloro-5-methylpyrimidine sigma4,6-Dichloro-5-methylpyrimidine manufacturer4,6-Dichloro-5-methylpyrimidine price4,6-Dichloro-5-methylpyrimidine structure4,6-Dichloro-5-methylpyrimidine SDSbuy 4,6-Dichloro-5-methylpyrimidine4,6-Dichloro-5-methylpyrimidine supplier4,6-Dichloro-5-methylpyrimidine uses4,6-Dichloro-5-methylpyrimidine molecular weightprice of 4,6-Dichloro-5-methylpyrimidine4,6-Dichloro-5-methylpyrimidine chemical name formula of 4,6-Dichloro-5-methylpyrimidine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4,6-Dichloro-5-methylpyrimidine

CAS No. 4316-97-6

Recommended Products