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CS-W001157 4
Total: USD 88.00

Cladribine

  • CAS No. 4291-63-8

  • Cat. No. CS-2057
  • Purity≥98%
  • MDL No.MFCD00153939

*For research and further manufacturing use only, not for direct human use.

Cladribine|CS-2057

Structure of 4291-63-8

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General Information

  • CAS No. 4291-63-8
  • Cat. No. CS-2057
  • Purity ≥98%
  • MDL No. MFCD00153939
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂ClN₅O₃
  • Molecular Weight None
  • Synonym(s) 2-Chloro-2′-deoxyadenosine; CldAdo; 2CdA
  • SMILES OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3=C2N=C(Cl)N=C3N)O1

Description

Copper catalyst for cross coupling.

Synthesis

  • Route1
    • null|null
      908006-51-9
    • null|null
      1266098-30-9
    • ~90%
    • In-stock
      Cladribine|CS-2057
      4291-63-8

    References

    • SCINOPHARM (KUNSHAN) BIOCHEMICAL TECHNOLOGY CO., LTD.; HENSCHKE, Julian, Paul; ZHANG, Xiaoheng; CHU, Guodong; MEI, Lijun; CHEN, Yungfa Patent: WO2011/20298 A1, 2011 ; Location in patent: Page/Page column 30-31 ;
  • Route2
    • null|null
      914084-44-9
    • ~71%
    • (2R,3S,5S)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol Cladribine Impurity|CS-0532404
      5542-92-7
    • In-stock
      Cladribine|CS-2057
      4291-63-8

    References

    • BRIGHAM YOUNG UNIVERSITY, TRANSFER TECHNOLOGY OFFICE Patent: WO2006/138396 A2, 2006 ; Location in patent: Page/Page column 61 ;
  • Route3
    • (2r,3s,5r)-5-(2,6-Dichloro-9h-purin-9-yl)-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate|CS-0664382
      38925-80-3
    • ~71%
    • In-stock
      Cladribine|CS-2057
      4291-63-8

    References

    • Kazimierczuk, Zygmunt; Cottam, Howard B.; Revankar, Ganapathi R.; Robins, Roland K. Journal of the American Chemical Society, 1984 , vol. 106, # 21 p. 6379 - 6382

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H341-H361-H372
Precautionary Statements : P260-P264-P270-P280-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   119.31
  • LogP   -0.2974
  • H_Acceptors   8
  • H_Donors   3
  • Rotatable_Bonds   2

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