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CS-W001157 4
Total: USD 88.00

(3-Ethoxy-3-oxopropyl)triphenylphosphonium bromide

  • CAS No. 42843-94-7

  • Cat. No. CS-W005866
  • Purity≥97%
  • MDL No.MFCD03701355

*For research and further manufacturing use only, not for direct human use.

(3-Ethoxy-3-oxopropyl)triphenylphosphonium bromide|CS-W005866

Structure of 42843-94-7

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General Information

  • CAS No. 42843-94-7
  • Cat. No. CS-W005866
  • Purity ≥97%
  • MDL No. MFCD03701355
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₂₄BrO₂P
  • Molecular Weight 443.31
  • Synonym(s) 2-(Ethoxycarbonyl)ethyltriphenylphosphoniumbromi
  • SMILES O=C(OCC)CC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Description

(3-Ethoxy-3-oxopropyl)triphenylphosphonium bromide delivers a reactive phosphonium moiety flanked by an ethoxy carbonyl group, enabling efficient Wittig-type olefination under mild conditions. This bench-stable reagent features enhanced solubility in polar aprotic solvents and facilitates the synthesis of functionalized alkenes with high stereoselectivity.

Application

(3-Ethoxy-3-oxopropyl)triphenylphosphonium bromide serves as a reliable Wittig reagent precursor, enabling the efficient synthesis of α,β-unsaturated carbonyl compounds. Its bench-stable nature and tolerance to common functional groups facilitate straightforward preparation of enones and conjugated aldehydes in standard organic transformations. The ethoxy carbonyl moiety enhances reactivity while maintaining compatibility with diverse reaction conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   26.3
  • LogP   0.9377
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   7

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