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CS-W001157 4
Total: USD 88.00

(2-Carboxyethyl)triphenylphosphonium bromide

  • CAS No. 51114-94-4

  • Cat. No. CS-M0693
  • Purity≥98%
  • MDL No.MFCD00031698

*For research and further manufacturing use only, not for direct human use.

(2-Carboxyethyl)triphenylphosphonium bromide|CS-M0693

Structure of 51114-94-4

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General Information

  • CAS No. 51114-94-4
  • Cat. No. CS-M0693
  • Purity ≥98%
  • MDL No. MFCD00031698
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₀BrO₂P
  • Molecular Weight 415.26
  • Synonym(s) (2-Carboxyethyl)tri
  • SMILES O=C(O)CC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Description

This triphenylphosphonium derivative delivers a targeted carboxyethyl group for mitochondrial delivery, combining lipophilic stability with enhanced aqueous solubility. The bromide counterion ensures high reactivity in conjugation workflows. Designed for bioconjugation and redox-active probe synthesis, it enables efficient cellular targeting through established phosphonium transport mechanisms.

Application

(2-Carboxyethyl)triphenylphosphonium bromide serves as a versatile phosphonium salt for the synthesis of Wittig-type reagents and functionalized alkenes. Its carboxylic acid group enables conjugation to biomolecules or incorporation into polymer backbones, while the triphenylphosphonium moiety facilitates efficient ylide formation under mild conditions. The compound exhibits good bench stability and is compatible with standard organic reaction protocols, offering reliable access to α,β-unsaturated systems in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   0.4592
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   6

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