(R)-(-)-1,2-Propanediol

Name: (R)-(-)-1,2-Propanediol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 4254-14-2
Cat. No. CS-W020032
Purity≥98%
MDL No.MFCD00066248

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 4254-14-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 4254-14-2
Cat. No. CS-W020032
Purity ≥98%
MDL No. MFCD00066248
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₈O₂
Molecular Weight 76.09
Synonym(s) None
SMILES C[C@@H](O)CO

Description

(R)-(-)-1,2-Propanediol is a chiral diol featuring a stereogenic center at the C2 position, offering high purity and stability under standard bench conditions. This enantiomerically pure compound integrates readily into asymmetric synthesis workflows, where its defined stereochemistry enables predictable reaction outcomes in catalytic transformations and derivatization processes.

Application

(R)-(-)-1,2-Propanediol serves as a chiral building block in asymmetric synthesis, offering predictable stereocontrol in transformations involving hydroxyl group functionalization. Its bench-stable nature and compatibility with common protecting group strategies facilitate reliable use in medicinal chemistry workflows. The molecule functions effectively in coupling reactions and as a scaffold for heterocyclic ring formation, supporting scalable applications in API development.

Synthesis

Route1
- 75-56-9
- ~49%
- In-stock
  
  4254-14-2
- 16088-62-3
References
- Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N. Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
Route2
- 20263-26-7
- ~99%
- In-stock
  
  4254-14-2
References
- Xing, Dongxia; Chen, Ping; Keil, Robert; Kilts, Clinton D.; Shi, Bing; Camp, Vernon M.; Malveaux, Gene; Ely, Timothy; Owens, Michael J.; Votaw, John; Davis, Margaret; Hoffman, John M.; BaKay, Roy A. E.; Subramanian, Thygarajan; Watts, Ray L.; Goodman, Mark M. Journal of Medicinal Chemistry, 2000 , vol. 43, # 4 p. 639 - 648
Route3
- 17392-83-5
- ~92%
- In-stock
  
  4254-14-2
References
- Kuriyama, Wataru; Matsumoto, Takaji; Ogata, Osamu; Ino, Yasunori; Aoki, Kunimori; Tanaka, Shigeru; Ishida, Kenya; Kobayashi, Tohru; Sayo, Noboru; Saito, Takao Organic Process Research and Development, 2012 , vol. 16, # 1 p. 166 - 171

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 40.46
LogP -0.6405
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Bioactive Molecules Natural Products

Building Blocks Skeleton Fatty chain compounds

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Analytical Science Drug Impurity Reference Substance Other Drugs Other impurity

Key Words

(R)-(-)-1,2-Propanediol sigma(R)-(-)-1,2-Propanediol manufacturer(R)-(-)-1,2-Propanediol price(R)-(-)-1,2-Propanediol structure(R)-(-)-1,2-Propanediol SDSbuy (R)-(-)-1,2-Propanediol(R)-(-)-1,2-Propanediol supplier(R)-(-)-1,2-Propanediol uses(R)-(-)-1,2-Propanediol molecular weightprice of (R)-(-)-1,2-Propanediol(R)-(-)-1,2-Propanediol chemical name formula of (R)-(-)-1,2-Propanediol

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-(-)-1,2-Propanediol

CAS No. 4254-14-2

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words