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Structure of 42413-03-6
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3-Chloro-4-methylbenzene-1-sulfonyl chloride features a sulfonyl chloride group flanked by electron-withdrawing chlorine and electron-donating methyl substituents, enabling selective acylation in synthetic workflows. This balance enhances reactivity while maintaining stability under standard bench conditions.
3-Chloro-4-methylbenzene-1-sulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of sulfonamide groups into pharmaceutical and agrochemical intermediates. Its ortho-chloro and meta-methyl substituents enhance reactivity while maintaining bench stability, enabling selective transformations with amines under mild conditions. The product facilitates clean, high-yielding amide bond formation and is compatible with common protecting group strategies in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H317-H412
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Precautionary Statements : P260-P261-P264-P272-P273-P280-P301+P330+P331-P302+P352-P304+P340-P362+P364-P363-P405-P501
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Lot numbers can be found on the outside label of a product: