N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide

Name: N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 42137-88-2
Cat. No. CS-0153042
Purity≥97%
MDL No.MFCD00018944

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide|CS-0153042

Structure of 42137-88-2

Size

Price

Quantity

* Please select Quantity before adding items.

Description

N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide features a sulfonamide core with two 2-chloroethyl substituents, enabling dual alkylating potential. The para-methyl group enhances electron density at the aromatic ring, improving stability under standard conditions. This compound functions as a bifunctional electrophile in targeted covalent labeling and crosslinking applications.

Application

N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide serves as a versatile bifunctional electrophile, enabling efficient sulfonamide-directed conjugate additions and tandem cyclizations. Its dual 2-chloroethyl groups facilitate rapid, high-yield intramolecular cyclization under mild conditions, forming stable heterocyclic scaffolds. Bench-stable and compatible with diverse functional groups, it functions as a key building block in the synthesis of complex sulfonamide-containing frameworks relevant to medicinal chemistry and process development.

General Information

CAS No. 42137-88-2
Cat. No. CS-0153042
Purity ≥97%
MDL No. MFCD00018944
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₅Cl₂NO₂S
Molecular Weight 296.21
Synonym(s) N,N-Bis-(2-chloroethyl)-p-toluenesulfonamide
SMILES CC1=CC=C(C=C1)S(=O)(=O)N(CCCl)CCCl

Computational Chemistry Data

TPSA 37.38
LogP 2.46332
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Building Blocks for Pharmaceutical Ingredients

Key Words

42137-88-2 sigma42137-88-2 manufacturer42137-88-2 price42137-88-2 structure42137-88-2 SDSbuy 42137-88-242137-88-2 supplier42137-88-2 uses42137-88-2 molecular weightprice of 42137-88-242137-88-2 chemical name formula of 42137-88-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

N,N-Bis(2-chloroethyl)-4-methylbenzenesulfonamide

CAS No. 42137-88-2

Recommended Products