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CS-W001157 4
Total: USD 88.00

3-Formyl-6-nitrochromone

  • CAS No. 42059-80-3

  • Cat. No. CS-0155777
  • Molecule weight219.15
  • Purity≥94%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Formyl-6-nitrochromone|CS-0155777

Structure of 42059-80-3

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General Information

  • CAS No. 42059-80-3
  • Cat. No. CS-0155777
  • Purity ≥94%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₅NO₅
  • Molecular Weight 219.15
  • Synonym(s) 6-NITROCHROMONE-3-CARBALDEHYDE
  • SMILES C1=CC2=C(C=C1[N+](=O)[O-])C(=O)C(=CO2)C=O

Description

3-Formyl-6-nitrochromone (6-Nitro-4-oxo-4H-1-benzopyran-3-carboxaldehyde) is a benzopyran derivative. It is a bicyclic heterocyclic molecule made up of a benzene ring fused to a heterocyclic pyran ring. 3-Formyl-6-nitrochromone has been reported to exhibit inhibitory activity against urease.3-Formyl-6-nitrochromone is the suitable reagent used in a study to investigate the multidrug resistance reversal by some 3- formylchromones in human colon cancer and mouse lymphoma cells transfected with the human MDR1 gene. It is the suitable reagent used in the synthesis of uridine-based library.

Synthesis

  • Route1
    • In-stock
      1-(2-Hydroxy-5-nitrophenyl)ethanone|CS-W002624
      1450-76-6
    • null|null
      68-12-2
    • ~92%
    • In-stock
      3-Formyl-6-nitrochromone|CS-0155777
      42059-80-3

    References

    • Organic Preparations and Procedures International, , vol. 39, # 5 p. 495 - 502
  • Route2
    • null|null
      100-02-7
    • ~%
    • In-stock
      3-Formyl-6-nitrochromone|CS-0155777
      42059-80-3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2855 - 2859
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 10 p. 2855 - 2859

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   90.42
  • LogP   1.5137
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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