Lot numbers can be found on the outside label of a product:
1-(2-Hydroxy-5-nitrophenyl)ethanone
-
CAS No. 1450-76-6
- Cat. No. CS-W002624
- Purity≥97%
- MDL No.MFCD00463816
*For research and further manufacturing use only, not for direct human use.
Structure of 1450-76-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 1450-76-6
- Cat. No. CS-W002624
- Purity ≥97%
- MDL No. MFCD00463816
- Storage 4°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₇NO₄
- Molecular Weight 181.15
- Synonym(s) 2-Hydroxy-5-nitroacetophenone
- SMILES [O-][N+](=O)c1ccc(c(c1)C(=O)C)O
Description
1-(2-Hydroxy-5-nitrophenyl)ethanone features a phenolic hydroxyl group flanked by a nitro substituent and a ketone functionality, enabling versatile participation in electrophilic and nucleophilic transformations. This arrangement supports efficient coupling reactions under mild conditions, particularly in the synthesis of functionalized aromatic scaffolds for medicinal chemistry applications.
Application
1-(2-Hydroxy-5-nitrophenyl)ethanone serves as a versatile building block in medicinal chemistry, enabling the synthesis of nitro-substituted phenolic scaffolds. Its dual functionality—phenolic hydroxyl and nitro group—facilitates downstream derivatization via coupling reactions, electrophilic substitution, or reduction to aniline intermediates. Bench-stable and amenable to standard purification techniques, it functions effectively in multi-step syntheses requiring regioselective functionalization.
Synthesis
-
Route1
-
100-02-7 -
75-36-5
- ~79%
-
In-stock
1450-76-6
References
-
DAEWOONG PHARMACEUTICAL CO., LTD. Patent: WO2006/109933 A1, 2006 ; Location in patent: Page/Page column 48 ;
-
-
Route2
-
In-stock
830-03-5 - ~94%
-
In-stock
1450-76-6
References
-
Kad; Trehan; Kaur; Nayyar; Arora; Brar Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 7 p. 734 - 736
-
-
Route3
-
118-93-4 - ~32%
-
In-stock
1450-76-6
-
In-stock
28177-69-7
References
-
Cushman, Mark; Zhu, Helen; Geahlen, Robert L.; Kraker, Alan J. Journal of Medicinal Chemistry, 1994 , vol. 37, # 20 p. 3353 - 3362
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 80.44
- LogP 1.503
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 1-(2-Hydroxy-5-nitrophenyl)ethanone sigma1-(2-Hydroxy-5-nitrophenyl)ethanone manufacturer1-(2-Hydroxy-5-nitrophenyl)ethanone price1-(2-Hydroxy-5-nitrophenyl)ethanone structure1-(2-Hydroxy-5-nitrophenyl)ethanone SDSbuy 1-(2-Hydroxy-5-nitrophenyl)ethanone1-(2-Hydroxy-5-nitrophenyl)ethanone supplier1-(2-Hydroxy-5-nitrophenyl)ethanone uses1-(2-Hydroxy-5-nitrophenyl)ethanone molecular weightprice of 1-(2-Hydroxy-5-nitrophenyl)ethanone1-(2-Hydroxy-5-nitrophenyl)ethanone chemical name formula of 1-(2-Hydroxy-5-nitrophenyl)ethanone