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CS-W001157 4
Total: USD 88.00

3-(Methylamino)propan-1-ol

  • CAS No. 42055-15-2

  • Cat. No. CS-W007469
  • Purity≥97%
  • MDL No.MFCD06797456

*For research and further manufacturing use only, not for direct human use.

3-(Methylamino)propan-1-ol|CS-W007469

Structure of 42055-15-2

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General Information

  • CAS No. 42055-15-2
  • Cat. No. CS-W007469
  • Purity ≥97%
  • MDL No. MFCD06797456
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁NO
  • Molecular Weight 89.14
  • Synonym(s) None
  • SMILES OCCCNC

Description

3-(Methylamino)propan-1-ol features a primary hydroxyl group flanked by a methylamino substituent, enabling versatile integration into bioconjugation and peptide synthesis workflows. This bifunctional scaffold combines nucleophilic amine reactivity with hydrophilic solubility, facilitating efficient coupling under mild conditions while maintaining stability during storage and handling.

Application

3-(Methylamino)propan-1-ol serves as a versatile bifunctional building block in synthetic organic chemistry, enabling the construction of bioactive heterocycles and peptide-like scaffolds. Its primary amine and hydroxyl groups offer orthogonal reactivity for selective derivatization, while its bench-stable nature facilitates straightforward purification and integration into multi-step syntheses. Functions effectively in amide couplings, cyclizations, and as a linker in medicinal chemistry campaigns.

Synthesis

  • Route1
    • null|null
      49807-74-1
    • ~87%
    • In-stock
      3-(Methylamino)propan-1-ol|CS-W007469
      42055-15-2

    References

    • WAKAMOTO PHARMACEUTICAL CO., LTD. Patent: WO2006/51851 A1, 2006 ; Location in patent: Page/Page column 77-78 ;
  • Route2
    • null|null
      58885-60-2
    • ~%
    • In-stock
      3-(Methylamino)propan-1-ol|CS-W007469
      42055-15-2

    References

    • Trapp, Sean G.; Leadbetter, Michael R.; Long, Daniel D.; Jiang, Lan; Axt, Sabine Patent: US2009/247627 A1, 2009 ; Location in patent: Page/Page column 17 ; US 20090247627 A1
  • Route3
    • 3-(Benzyl(methyl)amino)propan-1-ol|CS-0967206
      5814-42-6
    • ~61%
    • In-stock
      3-(Methylamino)propan-1-ol|CS-W007469
      42055-15-2

    References

    • Maslowska-Lipowicz, Iwona; Walczynski, Krzysztof Chemical Biology and Drug Design, 2014 , vol. 83, # 1 p. 106 - 118

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅱ
Hazard Statements : H227-H302-H314
Precautionary Statements : P210-P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.4118
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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