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CS-W001157 4
Total: USD 88.00

4-(Methylamino)butan-1-ol

  • CAS No. 42042-68-2

  • Cat. No. CS-W006493
  • Purity≥96%
  • MDL No.MFCD00673140

*For research and further manufacturing use only, not for direct human use.

4-(Methylamino)butan-1-ol|CS-W006493

Structure of 42042-68-2

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General Information

  • CAS No. 42042-68-2
  • Cat. No. CS-W006493
  • Purity ≥96%
  • MDL No. MFCD00673140
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃NO
  • Molecular Weight 103.16
  • Synonym(s) 4-Methylamino butanol
  • SMILES CNCCCCO

Description

4-(Methylamino)butan-1-ol features a primary alcohol group flanked by a methylamino substituent, offering enhanced solubility and metabolic stability. This amine-alcohol motif integrates readily into bioactive scaffolds, enabling efficient conjugation in peptide synthesis and drug discovery workflows.

Application

4-(Methylamino)butan-1-ol serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of amino alcohol scaffolds. Its primary amine and hydroxyl groups offer orthogonal reactivity for coupling, derivatization, and protecting group strategies. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in multi-step syntheses targeting bioactive compounds and heterocyclic intermediates.

Synthesis

  • Route1

    References

    • Wilk, Andrzej; Grajkowski, Andrzej; Phillips, Lawrence R.; Beaucage, Serge L. Journal of Organic Chemistry, 1999 , vol. 64, # 20 p. 7515 - 7522
  • Route2
    • null|null
      174656-73-6
    • ~%
    • In-stock
      4-(Methylamino)butan-1-ol|CS-W006493
      42042-68-2

    References

    • Low, G. K.-C.; Duffield, A. M. Organic Mass Spectrometry, 1985 , vol. 20, # 10 p. 595 - 599
  • Route3
    • In-stock
      4-Aminobutan-1-ol|CS-W002041
      13325-10-5
    • null|null
      109-94-4
    • ~54%
    • In-stock
      4-(Methylamino)butan-1-ol|CS-W006493
      42042-68-2

    References

    • UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.; PHANSTIEL IV, Otto; MUTH, Aaron Patent: WO2013/148230 A1, 2013 ; Location in patent: Page/Page column 29; 30 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.0217
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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