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Structure of 415973-05-6
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PyOxim [1] is a novel reagent which mediates coupling reactions with efficiencies superior to HATU and PyBOP and comparable to COMU. It is has excellent solubility in DMF and is stable in solution under an inert atmosphere for two days. Unlike HATU and HBTU, it cannot cause chain terminating side reactions and is, therefore, ideal for the synthesis of cyclic peptides. Furthermore, it is not explosive under normal operating conditions and is less likely to exhibit allergenicity compared to other coupling reagents.Associated Protocols and Technical ArticlesGuide to Selection of Coupling ReagentsLiterature references[1] R. Subiros-Funosas, et al. (2010) Org. Biomol. Chem., 8, 3665.
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GHS Pictogram :
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GHS No : GHS06,GHS09
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H300-H411
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Precautionary Statements : P264-P270-P273-P330-P391-P405-P501
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Lot numbers can be found on the outside label of a product: