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Structure of 415941-58-1
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This phosphine features a dimethylamino-substituted aryl group conjugated to a sterically shielded di-t-butylphosphine moiety, delivering enhanced stability and nucleophilicity. The electron-donating amine group amplifies phosphine basicity, while the bulky t-butyl groups inhibit oxidation and promote selectivity in catalytic transformations. Ideal for palladium-catalyzed cross-coupling reactions requiring robust, air-stable ligands under standard conditions.
[2-(N,N-Dimethylamino)phenyl]di-t-butylphosphine serves as a robust, bench-stable ligand in palladium-catalyzed cross-coupling reactions. Its electron-rich phosphine center enhances reactivity in Suzuki-Miyaura and Buchwald-Hartwig amination processes, while the bulky di-t-butyl groups provide steric protection and improve catalyst longevity. The ortho-dimethylaminophenyl moiety offers coordination versatility and facilitates handling in air-sensitive transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: