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CS-W001157 4
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N-(4-Bromo-3-(trifluoromethyl)phenyl)acetamide

  • CAS No. 41513-05-7

  • Cat. No. CS-0153980
  • Purity≥98%
  • MDL No.MFCD00052361

*For research and further manufacturing use only, not for direct human use.

N-(4-Bromo-3-(trifluoromethyl)phenyl)acetamide|CS-0153980

Structure of 41513-05-7

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General Information

  • CAS No. 41513-05-7
  • Cat. No. CS-0153980
  • Purity ≥98%
  • MDL No. MFCD00052361
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇BrF₃NO
  • Molecular Weight 282.06
  • Synonym(s) N-[4-Bromo-3-(trifluoromethyl)phenyl]acetamide
  • SMILES CC(NC1=CC(C(F)(F)F)=C(Br)C=C1)=O

Description

N-(4-Bromo-3-(trifluoromethyl)phenyl)acetamide features a brominated aryl core with a trifluoromethyl group enhancing electron deficiency, paired with a readily functionalizable acetamide handle. This combination enables efficient coupling reactions in synthetic routes to bioactive molecules and advanced materials.

Application

N-(4-Bromo-3-(trifluoromethyl)phenyl)acetamide serves as a versatile building block in medicinal chemistry, enabling the synthesis of biologically active aryl amides and heterocyclic scaffolds. The molecule combines a brominated aromatic ring with a trifluoromethyl group and an acetamide functionality, offering excellent stability and compatibility with Pd-catalyzed cross-coupling reactions. Its well-defined reactivity profile facilitates efficient derivatization, making it ideal for constructing complex pharmaceutical intermediates and functionalized arenes under standard synthetic conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   3.4263
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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