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CS-W001157 4
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4-Methylpiperidine-1-sulfonyl chloride

  • CAS No. 41483-70-9

  • Cat. No. CS-0152677
  • Purity≥95%
  • MDL No.MFCD08445024

*For research and further manufacturing use only, not for direct human use.

4-Methylpiperidine-1-sulfonyl chloride|CS-0152677

Structure of 41483-70-9

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General Information

  • CAS No. 41483-70-9
  • Cat. No. CS-0152677
  • Purity ≥95%
  • MDL No. MFCD08445024
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClNO₂S
  • Molecular Weight 197.68
  • Synonym(s) 4-Methyl-piperidine-1-sulfonyl chloride
  • SMILES CC1CCN(CC1)S(=O)(=O)Cl

Description

4-Methylpiperidine-1-sulfonyl chloride delivers a reactive sulfonyl chloride group tethered to a sterically accessible piperidine scaffold, enabling efficient incorporation into bioactive molecules. This bench-stable derivative facilitates rapid conjugation in synthetic workflows requiring selective amine coupling under mild conditions.

Application

4-Methylpiperidine-1-sulfonyl chloride serves as a versatile sulfonylating agent for the efficient introduction of sulfonamide groups into organic frameworks. It enables rapid functionalization of amines under mild conditions, offering high reactivity and excellent yield in amide bond formation. The molecule's bench-stable nature and compatibility with diverse functional groups make it well-suited for medicinal chemistry lead optimization and API intermediate synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H301-H311-H314-H331
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P405-P501

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Computational Chemistry Data

  • TPSA   37.38
  • LogP   1.2019
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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