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CS-W001157 4
Total: USD 88.00

2-Chloro-1-iodo-4-nitrobenzene

  • CAS No. 41252-96-4

  • Cat. No. CS-0157167
  • Purity≥96%
  • MDL No.MFCD00024589

*For research and further manufacturing use only, not for direct human use.

2-Chloro-1-iodo-4-nitrobenzene|CS-0157167

Structure of 41252-96-4

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General Information

  • CAS No. 41252-96-4
  • Cat. No. CS-0157167
  • Purity ≥96%
  • MDL No. MFCD00024589
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClINO₂
  • Molecular Weight 283.45
  • Synonym(s) 3-CHLORO-4-IODONITROBENZENE
  • SMILES C1=CC(=C(C=C1[N+](=O)[O-])Cl)I

Description

THP-SS-PEG1-Tos is a cleavable linker containing a THP protecting group and a tosyl end group. Tos is a good leaving group by reacting with nucleophiles, The disulfide bonds can be cleaved by using Dithiothreitol (DTT) reagent.

Synthesis

  • Route1
    • null|null
      121-87-9
    • ~%
    • In-stock
      2-Chloro-1-iodo-4-nitrobenzene|CS-0157167
      41252-96-4

    References

    • Sato, Motohide; Kawakami, Hiroshi; Motomura, Takahisa; Aramaki, Hisateru; Matsuda, Takashi; Yamashita, Masaki; Ito, Yoshiharu; Matsuzaki, Yuji; Yamataka, Kazunobu; Ikeda, Satoru; Shinkai, Hisashi Journal of Medicinal Chemistry, 2009 , vol. 52, # 15 p. 4869 - 4882
  • Route2
    • null|null
      401631-87-6
    • ~76%
    • null|null
      121-73-3
    • In-stock
      2-Chloro-1-iodo-4-nitrobenzene|CS-0157167
      41252-96-4

    References

    • Barbero; Degani; Diulgheroff; Dughera; Fochi Synthesis, 2001 , # 14 p. 2180 - 2190
  • Route3
    • null|null
      24616-42-0
    • ~%
    • In-stock
      2-Chloro-1-iodo-4-nitrobenzene|CS-0157167
      41252-96-4

    References

    • Saeki, Tomoyuki; Son, Eun-Cheol; Tamao, Kohei Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 9 p. 1654 - 1658

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.14
  • LogP   2.8528
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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