Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Chloro-2-iodo-3-nitrobenzene

  • CAS No. 32337-97-6

  • Cat. No. CS-0041171
  • Purity≥96%
  • MDL No.MFCD08275977

*For research and further manufacturing use only, not for direct human use.

1-Chloro-2-iodo-3-nitrobenzene|CS-0041171

Structure of 32337-97-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 32337-97-6
  • Cat. No. CS-0041171
  • Purity ≥96%
  • MDL No. MFCD08275977
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃ClINO₂
  • Molecular Weight 283.45
  • Synonym(s) 3-chloro-2-iodonitrobenzene
  • SMILES O=[N+](C1=C(I)C(Cl)=CC=C1)[O-]

Description

1-Chloro-2-iodo-3-nitrobenzene features a tri-substituted benzene core with orthogonal reactivity profiles. The electron-deficient aromatic ring enables palladium-catalyzed cross-coupling, while the iodine moiety serves as a high-efficiency coupling handle. This compound integrates seamlessly into complex molecular architectures under mild conditions.

Application

1-Chloro-2-iodo-3-nitrobenzene serves as a versatile dihalogenated building block for palladium-catalyzed cross-coupling reactions, enabling sequential functionalization at distinct aromatic positions. The chloro group facilitates Suzuki-Miyaura coupling, while the iodo moiety supports efficient Stille or Negishi transformations under mild conditions. Its nitro functionality provides a handle for selective reduction and downstream heterocycle formation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • Sohn, Jungsan; Kiburz, Brendan; Li, Zhitao; Deng, Liu; Safi, Alexias; Pirrung, Michael C.; Rudolph, Johannes Journal of Medicinal Chemistry, 2003 , vol. 46, # 13 p. 2580 - 2588
  • Route2
    • null|null
      121-73-3
    • ~%
    • In-stock
      1-Chloro-2-iodo-3-nitrobenzene|CS-0041171
      32337-97-6

    References

    • MERCK SHARP and DOHME CORP.; ElexoPharm GmbH; HOYT, Scott, B.; PETRILLI, Whitney Lane; LONDON, Clare; XIONG, Yusheng; TAYLOR, Jerry Andrew; ALI, Amjad; LO, Michael; HENDERSON, Timothy, J.; HU, Qingzhong; HARTMANN, Rolf; YIN, Lina; HEIM, Ralf; BEY, Emmanuel; SAXENA, Rohit; SAMANTA, Swapan Kumar; KULKARNI, Bheemashankar, A. Patent: WO2012/148808 A1, 2012 ; WO 2012/148808 A1
  • Route3
    • null|null
      602-02-8
    • ~%
    • In-stock
      1-Chloro-2-iodo-3-nitrobenzene|CS-0041171
      32337-97-6

    References

    • Wallagh; Wibaut Recueil des Travaux Chimiques des Pays-Bas, 1936 , vol. 55, p. 1071,1073

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   43.14
  • LogP   2.8528
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Chloro-2-iodo-3-nitrobenzene sigma1-Chloro-2-iodo-3-nitrobenzene manufacturer1-Chloro-2-iodo-3-nitrobenzene price1-Chloro-2-iodo-3-nitrobenzene structure1-Chloro-2-iodo-3-nitrobenzene SDSbuy 1-Chloro-2-iodo-3-nitrobenzene1-Chloro-2-iodo-3-nitrobenzene supplier1-Chloro-2-iodo-3-nitrobenzene uses1-Chloro-2-iodo-3-nitrobenzene molecular weightprice of 1-Chloro-2-iodo-3-nitrobenzene1-Chloro-2-iodo-3-nitrobenzene chemical name formula of 1-Chloro-2-iodo-3-nitrobenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label