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CS-W001157 4
Total: USD 88.00

4-Methyl-6-methoxyquinoline

  • CAS No. 41037-26-7

  • Cat. No. CS-W017550
  • Purity≥98%
  • MDL No.MFCD00191547

*For research and further manufacturing use only, not for direct human use.

4-Methyl-6-methoxyquinoline|CS-W017550

Structure of 41037-26-7

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General Information

  • CAS No. 41037-26-7
  • Cat. No. CS-W017550
  • Purity ≥98%
  • MDL No. MFCD00191547
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁NO
  • Molecular Weight 173.22
  • Synonym(s) 6-Methoxy-4-methylquinoline
  • SMILES COC1=CC=C2N=CC=C(C)C2=C1

Description

4-Methyl-6-methoxyquinoline is a heterocyclic compound featuring a quinoline core substituted with a methyl group at the 4-position and a methoxy group at the 6-position. This combination imparts enhanced electron-donating character and improved solubility in organic solvents, making it valuable for constructing advanced ligands and fluorescent probes in photonic materials and medicinal chemistry applications.

Application

4-Methyl-6-methoxyquinoline serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its electron-rich quinoline core enables efficient Pd-catalyzed cross-coupling reactions, while the methyl and methoxy groups provide orthogonal functional handles for further derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting bioactive scaffolds and optoelectronic materials.

Synthesis

  • Route1
    • null|null
      104-94-9
    • null|null
      78-94-4
    • ~84%
    • In-stock
      4-Methyl-6-methoxyquinoline|CS-W017550
      41037-26-7

    References

    • Sivaprasad, Ganesabaskaran; Rajesh, Rengasamy; Perumal, Paramasivan T. Tetrahedron Letters, 2006 , vol. 47, # 11 p. 1783 - 1785
  • Route2
    • null|null
      1384466-92-5
    • ~82%
    • In-stock
      4-Methyl-6-methoxyquinoline|CS-W017550
      41037-26-7

    References

    • Kobayashi, Yuichi; Igarashi, Junji; Feng, Chao; Toshifumi; Tojo Tetrahedron Letters, 2012 , vol. 53, # 29 p. 3742 - 3745
  • Route3
    • null|null
      675578-57-1
    • ~10%
    • In-stock
      4-Methyl-6-methoxyquinoline|CS-W017550
      41037-26-7

    References

    • Theeraladanon, Chumpol; Arisawa, Mitsuhiro; Nishida, Atsushi; Nakagawa, Masako Tetrahedron, 2004 , vol. 60, # 13 p. 3017 - 3035

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.55182
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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