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CS-W001157 4
Total: USD 88.00

2,3-Dihydro-1H-indene

  • CAS No. 496-11-7

  • Cat. No. CS-W016586
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydro-1H-indene|CS-W016586

Structure of 496-11-7

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General Information

  • CAS No. 496-11-7
  • Cat. No. CS-W016586
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀
  • Molecular Weight 118.18
  • Synonym(s) Hydrindene
  • SMILES C12=C(CCC2)C=CC=C1

Description

N-(Azido-PEG4)-biocytin is a biotin PEG linker containing a carboxylic group and an azide group. Reaction of carboxylic with primary amino (-NH2) forms stable, irreversible amide bonds. The azide group can react with alkyne moiety in Cu(I)-catalyzed Click Chemistry reaction or DBCO moiety in copper-free Click Chemistry reaction to form a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media of the molecules conjugated to the biotin compound.

Synthesis

  • Route1
    • 1-Indanone Rasagiline  Impurity|CS-0229098
      83-33-0
    • ~94%
    • In-stock
      2,3-Dihydro-1H-indene|CS-W016586
      496-11-7

    References

    • Olah, George A.; Arvanaghi, Massoud; Ohannesian, Lena Synthesis, 1986 , # 9 p. 770 - 772
  • Route2
    • null|null
      108-88-3
    • ~%
    • In-stock
      2,3-Dihydro-1H-indene|CS-W016586
      496-11-7
    • null|null
      71-43-2

    References

    • China Petroleum and Chemical Corporation; Shanghai Research Institute of Petrochemical Technology Sinopec Patent: US2004/186332 A1, 2004 ; Location in patent: Page 4-6 ;
  • Route3
    • In-stock
      1-Allyl-2-bromobenzene,98% (stabilized with MEHQ)|CS-0157945
      42918-20-7
    • null|null
      280-64-8
    • ~85%
    • In-stock
      2,3-Dihydro-1H-indene|CS-W016586
      496-11-7

    References

    • Miyaura, Norio; Ishiyama, Tatsuo; Sasaki, Hirotomo; Ishikawa, Masako; Satoh, Makoto; Suzuki, Akira Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 314 - 321

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS08
Signal Word : Danger
UN#: 3295
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H304-H412
Precautionary Statements : P210-P233-P240-P241-P242-P243-P273-P280-P331-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.1753
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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