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CS-W001157 4
Total: USD 88.00

Thionicotinamide adenine dinucleotide

  • CAS No. 4090-29-3

  • Cat. No. CS-0143572
  • Purity≥98%
  • MDL No.MFCD00079609

*For research and further manufacturing use only, not for direct human use.

Thionicotinamide adenine dinucleotide|CS-0143572

Structure of 4090-29-3

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General Information

  • CAS No. 4090-29-3
  • Cat. No. CS-0143572
  • Purity ≥98%
  • MDL No. MFCD00079609
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₇N₇O₁₃P₂S
  • Molecular Weight 679.49
  • Synonym(s) Thio-NAD
  • SMILES NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]4O)[N+]5=CC(C(N)=S)=CC=C5)[C@H]4O)([O-])=O)(O)=O)O3

Description

Altering redox-sensitive enzyme kinetics via thione substitution, Thionicotinamide adenine dinucleotide (CAS 4090-29-3) enables sensitive detection in dual-enzyme cycling ELISAs for SARS-CoV-2 spike glycoprotein and live M. tuberculosis in sputum samples through distinct 405 nm absorbance.

Application

Thionicotinamide adenine dinucleotide (CAS 4090-29-3) drives S-adenosyl-L-homocysteine hydrolase inhibition assays by acting as a precise substrate analog that mimics NAD+ in catalytic sites. It reveals enzyme kinetics with high fidelity. Researchers leverage this to probe NAD+ glycohydrolase activity and dissect metabolic regulation in methylation pathways.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   304.02
  • LogP   -3.1126
  • H_Acceptors   18
  • H_Donors   7
  • Rotatable_Bonds   11

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