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CS-W001157 4
Total: USD 88.00

4-Bromo-3-methylpyridine hydrochloride

  • CAS No. 40899-37-4

  • Cat. No. CS-W003204
  • Purity≥95%
  • MDL No.MFCD04966778

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-methylpyridine hydrochloride|CS-W003204

Structure of 40899-37-4

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General Information

  • CAS No. 40899-37-4
  • Cat. No. CS-W003204
  • Purity ≥95%
  • MDL No. MFCD04966778
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrClN
  • Molecular Weight 208.48
  • Synonym(s) Nsc235794
  • SMILES Cc1cnccc1Br.Cl

Description

4-Bromo-3-methylpyridine hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a bromine atom at the 4-position and a methyl group at the 3-position of the pyridine ring. This configuration enables selective cross-coupling reactions and facilitates incorporation into pharmaceutical scaffolds requiring electron-deficient aromatic cores.

Application

4-Bromo-3-methylpyridine hydrochloride serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the bromine site. The pyridyl nitrogen and methyl group offer orthogonal functionalization potential, while the hydrochloride salt enhances bench stability and simplifies handling. Its compatibility with standard synthetic protocols facilitates efficient construction of heterocyclic scaffolds and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.57432
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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