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CS-W001157 4
Total: USD 88.00

2-Aminomethylphenylacetic acid

  • CAS No. 40851-65-8

  • Cat. No. CS-W023054
  • Purity≥97%
  • MDL No.MFCD04038440

*For research and further manufacturing use only, not for direct human use.

2-Aminomethylphenylacetic acid|CS-W023054

Structure of 40851-65-8

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General Information

  • CAS No. 40851-65-8
  • Cat. No. CS-W023054
  • Purity ≥97%
  • MDL No. MFCD04038440
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁NO₂
  • Molecular Weight 165.19
  • Synonym(s) 2-aminomethylphenylacetic acid(intermediate of ceforanide)
  • SMILES O=C(O)CC1=CC=CC=C1CN

Description

2-Aminomethylphenylacetic acid features a strategically positioned amine-bearing side chain attached to a phenylacetic core, enabling direct conjugation or metal coordination in bioconjugation and catalyst design. This scaffold integrates readily into peptide architectures and functional materials under standard conditions.

Application

2-Aminomethylphenylacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-aminomethyl functionality facilitates efficient cyclization reactions, while the carboxylic acid group supports straightforward derivatization. The compound exhibits good bench stability and compatibility with standard coupling protocols, making it well-suited for iterative synthesis workflows in API development.

Synthesis

  • Route1
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      40851-64-7
    • ~%
    • In-stock
      2-Aminomethylphenylacetic acid|CS-W023054
      40851-65-8

    References

    • Tetrahedron Letters, , vol. 39, # 27 p. 4773 - 4776
  • Route2
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      170306-38-4
    • ~%
    • In-stock
      2-Aminomethylphenylacetic acid|CS-W023054
      40851-65-8

    References

    • Justus Liebigs Annalen der Chemie, , vol. 445, p. 246
  • Route3
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      861338-62-7
    • ~%
    • In-stock
      2-Aminomethylphenylacetic acid|CS-W023054
      40851-65-8

    References

    • Justus Liebigs Annalen der Chemie, , vol. 445, p. 246

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   0.7724
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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