Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Nitro-2-(trifluoromethyl)phenylboronic acid

  • CAS No. 408359-15-9

  • Cat. No. CS-0178342
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Nitro-2-(trifluoromethyl)phenylboronic acid|CS-0178342

Structure of 408359-15-9

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

4-Nitro-2-(trifluoromethyl)phenylboronic acid features a para-nitro group and ortho-trifluoromethyl substituent that enhance electronic withdrawal, enabling efficient Suzuki-Miyaura coupling under mild conditions. This bench-stable boronic acid integrates readily into complex molecular architectures with high functional group tolerance.

Application

4-Nitro-2-(trifluoromethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The nitro and trifluoromethyl groups provide orthogonal reactivity and enhanced electronic modulation, while the boronic acid functionality offers excellent bench stability and compatibility with diverse reaction partners. Its predictable coupling behavior and ease of purification make it a practical choice for medicinal chemistry and materials synthesis workflows.

General Information

  • CAS No. 408359-15-9
  • Cat. No. CS-0178342
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BF₃NO₄
  • Molecular Weight 234.93
  • Synonym(s) Boronic acid, [4-nitro-2-(trifluoromethyl)phenyl]- (9CI)
  • SMILES OB(C1=CC=C([N+]([O-])=O)C=C1C(F)(F)F)O

Computational Chemistry Data

  • TPSA   83.6
  • LogP   0.2934
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 408359-15-9 sigma408359-15-9 manufacturer408359-15-9 price408359-15-9 structure408359-15-9 SDSbuy 408359-15-9408359-15-9 supplier408359-15-9 uses408359-15-9 molecular weightprice of 408359-15-9408359-15-9 chemical name formula of 408359-15-9
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label