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Structure of 408359-15-9
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4-Nitro-2-(trifluoromethyl)phenylboronic acid features a para-nitro group and ortho-trifluoromethyl substituent that enhance electronic withdrawal, enabling efficient Suzuki-Miyaura coupling under mild conditions. This bench-stable boronic acid integrates readily into complex molecular architectures with high functional group tolerance.
4-Nitro-2-(trifluoromethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. The nitro and trifluoromethyl groups provide orthogonal reactivity and enhanced electronic modulation, while the boronic acid functionality offers excellent bench stability and compatibility with diverse reaction partners. Its predictable coupling behavior and ease of purification make it a practical choice for medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: