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CS-W001157 4
Total: USD 88.00

Z-Lys(Z)-OH

  • CAS No. 405-39-0

  • Cat. No. CS-W009697
  • Molecule weight414.45
  • Purity≥96%
  • MDL No.MFCD00037822

*For research and further manufacturing use only, not for direct human use.

Z-Lys(Z)-OH|CS-W009697

Structure of 405-39-0

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General Information

  • CAS No. 405-39-0
  • Cat. No. CS-W009697
  • Purity ≥96%
  • MDL No. MFCD00037822
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₂H₂₆N₂O₆
  • Molecular Weight 414.45
  • Synonym(s) None
  • SMILES O=C([C@@H](NC(OCC1=CC=CC=C1)=O)CCCCNC(OCC2=CC=CC=C2)=O)O

Description

Z-Lys(Z)-OH is a protected lysine derivative featuring a benzoyl group on the α-amino nitrogen and a benzyloxycarbonyl (Z) group on the side-chain amine. This dual protection enables selective coupling in peptide synthesis, offering enhanced stability and compatibility with standard activation protocols. The Z-protected side chain prevents unwanted reactions during chain elongation.

Synthesis

  • Route1
    • In-stock
      L-Lys-OH Amino acid impurity|CS-1733140
      56-87-1
    • null|null
      501-53-1
    • ~97%
    • In-stock
      Z-Lys(Z)-OH|CS-W009697
      405-39-0

    References

    • Chu, Benjamin Patent: US2006/94673 A1, 2006 ; Location in patent: Page/Page column 4 ;
  • Route2
    • null|null
      144889-39-4
    • ~84%
    • In-stock
      Z-Lys(Z)-OH|CS-W009697
      405-39-0

    References

    • Mehta, Anita; Jaouhari, Rabih; Benson, Timothy J.; Douglas, Kenneth T. Tetrahedron Letters, 1992 , vol. 33, # 37 p. 5441 - 5444
  • Route3

    References

    • Yang, Jianxin; Zhao, Kang; Gong, Youxiang; Vologodskii, Alexander; Kallenbach, Neville R. Journal of the American Chemical Society, 1998 , vol. 120, # 41 p. 10646 - 10652

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   113.96
  • LogP   3.4627
  • H_Acceptors   5
  • H_Donors   3
  • Rotatable_Bonds   11

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