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CS-W001157 4
Total: USD 88.00

1-(4-Fluorophenyl)-2-hydroxy-1-ethanone

  • CAS No. 403-31-6

  • Cat. No. CS-0213503
  • Purity≥95%
  • MDL No.MFCD02679035

*For research and further manufacturing use only, not for direct human use.

1-(4-Fluorophenyl)-2-hydroxy-1-ethanone|CS-0213503

Structure of 403-31-6

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General Information

  • CAS No. 403-31-6
  • Cat. No. CS-0213503
  • Purity ≥95%
  • MDL No. MFCD02679035
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇FO₂
  • Molecular Weight 154.14
  • Synonym(s) p-Fluorophenacyl alcohol
  • SMILES C1=C(C=CC(=C1)F)C(=O)CO

Synthesis

  • Route1
    • 2-(4-Fluorophenyl)-2-oxoethyl acetate|CS-0323347
      366-78-9
    • ~85%
    • 1-(4-Fluorophenyl)-2-hydroxy-1-ethanone|CS-0213503
      403-31-6

    References

    • Zhejiang Hisun Pharmaceutical Co. Ltd. Patent: EP2465847 A1, 2012 ; Location in patent: Page/Page column 14; 15 ;
  • Route2

    References

    • Nique, Francois; Hebbe, Severine; Triballeau, Nicolas; Peixoto, Christophe; Lefrancois, Jean-Michel; Jary, Helene; Alvey, Luke; Manioc, Murielle; Housseman, Christopher; Klaassen, Hugo; Van Beeck, Kris; Guedin, Denis; Namour, Florence; Minet, Dominque; Van Der Aar, Ellen; Feyen, Jean; Fletcher, Stephen; Blanque, Roland; Robin-Jagerschmidt, Catherine; Deprez, Pierre Journal of Medicinal Chemistry, 2012 , vol. 55, # 19 p. 8236 - 8247,12 Title/Abstract Full Text Show Details Nique, Francois; Hebbe, Severine; Triballeau, Nicolas; Peixoto, Christophe; Lefrancois, Jean-Michel; Jary, Helene; Alvey, Luke; Manioc, Murielle; Housseman, Christopher; Klaassen, Hugo; Van Beeck, Kris; Guedin, Denis; Namour, Florence; Minet, Dominque; Van Der Aar, Ellen; Feyen, Jean; Fletcher, Stephen; Blanque, Roland; Robin-Jagerschmidt, Catherine; Deprez, Pierre Journal of Medicinal Chemistry, 2012 , vol. 55, # 19 p. 8236 - 8247
  • Route3

    References

    • Moriarty, Robert M.; Hu, Henry; Gupta, Satish C. Tetrahedron Letters, 1981 , vol. 22, # 14 p. 1283 - 1286

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅲ
Hazard Statements : H228-H315-H319-H335
Precautionary Statements : P210-P240-P241-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.0007
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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