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CS-W001157 4
Total: USD 88.00

α-(4-Isobutylphenyl)ethanol

  • CAS No. 40150-92-3

  • Cat. No. CS-0154242
  • Purity≥98%
  • MDL No.MFCD08275597

*For research and further manufacturing use only, not for direct human use.

α-(4-Isobutylphenyl)ethanol|CS-0154242

Structure of 40150-92-3

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General Information

  • CAS No. 40150-92-3
  • Cat. No. CS-0154242
  • Purity ≥98%
  • MDL No. MFCD08275597
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₈O
  • Molecular Weight 178.27
  • Synonym(s) 1-(4-Isobutylphenyl)ethanol
  • SMILES CC(C)CC1=CC=C(C=C1)C(C)O

Description

α-(4-Isobutylphenyl)ethanol features a bulky isobutyl group that imparts steric shielding and enhances metabolic stability. This aryl-alcohol scaffold integrates readily into chiral syntheses and serves as a key intermediate in pharmaceutical development, offering improved solubility and handling under standard conditions.

Synthesis

  • Route1
    • 4'-Isobutylacetophenone Ibuprofen Impurity|CS-0228883
      38861-78-8
    • ~99%
    • In-stock
      α-(4-Isobutylphenyl)ethanol|CS-0154242
      40150-92-3

    References

    • Sawada; Okada; Kuroda; Watanabe; Tanaka Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 7 p. 799 - 813
  • Route2
    • null|null
      538-93-2
    • 4'-Isobutylacetophenone Ibuprofen Impurity|CS-0228883
      38861-78-8
    • ~%
    • In-stock
      α-(4-Isobutylphenyl)ethanol|CS-0154242
      40150-92-3

    References

    • HOECHST CELANESE CORPORATION Patent: EP284310 B1, 1991 ;
  • Route3
    • In-stock
      Ibuprofen|CS-1931
      15687-27-1
    • ~52%
    • 4'-Isobutylacetophenone Ibuprofen Impurity|CS-0228883
      38861-78-8
    • In-stock
      α-(4-Isobutylphenyl)ethanol|CS-0154242
      40150-92-3
    • null|null
      69474-20-0

    References

    • Komuro, Masakatsu; Nagatsu, Yoshio; Higuchi, Tsunehiko; Hirobe, Masaaki Tetrahedron Letters, 1992 , vol. 33, # 34 p. 4949 - 4952

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.9384
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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