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CS-W001157 4
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L-Arginine p-nitroanilide dihydrochloride, 98%

  • CAS No. 40127-11-5

  • Cat. No. CS-0142663
  • Molecule weight367.23
  • Purity≥97%
  • MDL No.MFCD00058249

*For research and further manufacturing use only, not for direct human use.

L-Arginine p-nitroanilide dihydrochloride, 98%|CS-0142663

Structure of 40127-11-5

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General Information

  • CAS No. 40127-11-5
  • Cat. No. CS-0142663
  • Purity ≥97%
  • MDL No. MFCD00058249
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₀Cl₂N₆O₃
  • Molecular Weight 367.23
  • Synonym(s) H-Arg-pNA 2HCl, 98%
  • SMILES O=C(NC1=CC=C([N+]([O-])=O)C=C1)[C@@H](N)CCCNC(N)=N.Cl.Cl

Description

L-Arginine p-nitroanilide dihydrochloride features a reactive p-nitroanilide ester moiety that enables efficient coupling in peptide synthesis. This bench-stable derivative facilitates controlled amide bond formation under standard conditions, offering reliable performance in enzymatic assays and bioconjugation workflows.

Application

L-Arginine p-nitroanilide dihydrochloride (CAS 40127-11-5) drives nitric oxide synthase activity assays by acting as a sensitive chromogenic substrate in real-time kinetic studies. This enables precise monitoring of enzyme function. Researchers leverage this to decode vascular signaling, refine drug formulations for cardiovascular health, and develop diagnostic tools targeting nitric oxide metabolism disorders.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   160.16
  • LogP   0.96747
  • H_Acceptors   5
  • H_Donors   5
  • Rotatable_Bonds   7

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