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Structure of 400777-00-6
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tert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamate serves as a pivotal building block in the synthesis of functionalized pyridine derivatives. The iodide moiety enables efficient late-stage diversification via palladium-catalyzed cross-coupling, while the tert-butoxycarbonyl group provides robust protection for the pyridinic nitrogen. This combination delivers enhanced stability and solubility under standard reaction conditions, streamlining access to complex heterocyclic architectures.
tert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamate serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable iodo functionality. The protected amine and orthogonal chloro substituent facilitate sequential functionalization, while the tert-butyl carbamate group offers bench stability and ease of removal under mild acidic conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: