Lot numbers can be found on the outside label of a product:
N-Boc-3-Amino-4-iodopyridine
-
CAS No. 154048-89-2
- Cat. No. CS-M1250
- Purity≥96%
- MDL No.MFCD04973410
*For research and further manufacturing use only, not for direct human use.
Structure of 154048-89-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 154048-89-2
- Cat. No. CS-M1250
- Purity ≥96%
- MDL No. MFCD04973410
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₁₃IN₂O₂
- Molecular Weight 320.13
- Synonym(s) (4-Iodo-pyridin-3-YL)-carbamic acid tert-butyl ester
- SMILES O=C(OC(C)(C)C)NC(C=NC=C1)=C1I
Description
N-Boc-3-Amino-4-iodopyridine features a protected amine and a reactive iodide handle, enabling efficient coupling in cross-coupling reactions. The electron-deficient pyridine ring enhances reactivity, while the Boc group ensures stability during storage and handling. This compound serves as a key building block for functionalized heterocycles in medicinal chemistry and materials science applications.
Application
N-Boc-3-Amino-4-iodopyridine serves as a versatile building block for the synthesis of iodinated pyridine scaffolds in medicinal chemistry and catalytic cross-coupling workflows. The Boc-protected amine enables stable handling and orthogonal deprotection, while the iodo group facilitates reliable Suzuki, Stille, or Negishi couplings. Its functional group tolerance and bench stability support efficient access to complex heterocycles and API intermediates.
Synthesis
-
Route1
-
In-stock
56700-70-0 - ~69%
-
In-stock
154048-89-2
References
-
F. HOFFMANN-LA ROCHE AG; BISSANTZ, Caterina; DEHMLOW, Henrietta; ERICKSON, Shawn David; KARNACHI, Prabha Saba; KIM, Kyungjin; MARTIN, Rainerm, E.; MATTEI, Patrizio; OBST SANDER, Ulrike; PIETRANICO-COLE, Sherrie Lynn; RICHTER, Hans; ULLMER, Christoph Patent: WO2012/117000 A1, 2012 ; Location in patent: Page/Page column 157; 158 ;
-
-
Route2
-
109-72-8 -
20485-44-3
-
In-stock
56700-70-0
- ~%
-
In-stock
154048-89-2
References
-
US2003/78277 A1, ;
-
-
Route3
-
462-08-8
- ~%
-
In-stock
154048-89-2
References
-
Heterocycles, , vol. 51, # 4 p. 721 - 726
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 51.22
- LogP 3.0332
- H_Acceptors 3
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- N-Boc-3-Amino-4-iodopyridine sigmaN-Boc-3-Amino-4-iodopyridine manufacturerN-Boc-3-Amino-4-iodopyridine priceN-Boc-3-Amino-4-iodopyridine structureN-Boc-3-Amino-4-iodopyridine SDSbuy N-Boc-3-Amino-4-iodopyridineN-Boc-3-Amino-4-iodopyridine supplierN-Boc-3-Amino-4-iodopyridine usesN-Boc-3-Amino-4-iodopyridine molecular weightprice of N-Boc-3-Amino-4-iodopyridineN-Boc-3-Amino-4-iodopyridine chemical name formula of N-Boc-3-Amino-4-iodopyridine