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Structure of 400755-41-1
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3-Methoxy-4-nitro-1H-pyrazole is a bench-stable heterocyclic scaffold featuring complementary electron-withdrawing and electron-donating substituents. The para-oriented nitro group enhances electrophilicity at the pyrazole ring, while the methoxy moiety contributes resonance donation, enabling tunable reactivity in cross-coupling and cycloaddition processes. This balanced electronic profile supports efficient integration into complex molecular architectures under standard conditions.
3-Methoxy-4-nitro-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive compounds through selective functionalization at the pyrazole core. The methoxy group enhances solubility and modulates electronic properties, while the nitro substituent provides a handle for reductive transformations or nucleophilic displacement. This compound exhibits bench stability and compatibility with standard coupling reactions, facilitating efficient incorporation into complex scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: