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Structure of 400-66-8
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2-Bromo-4-nitro-6-(trifluoromethyl)aniline features a trifluoromethyl group that enhances electron withdrawal, while the bromo and nitro substituents enable efficient coupling reactions. This aniline derivative serves as a key intermediate in pharmaceutical synthesis, offering high stability under standard conditions and compatibility with palladium-catalyzed transformations.
2-Bromo-4-nitro-6-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromo functionality. The nitro group facilitates subsequent reduction and cyclization pathways, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. Its bench-stable nature and compatibility with diverse functional groups support efficient route development for complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: