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Structure of 39891-82-2
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trans-2-Cyanocyclopropane-1-carboxylic acid features a strained cyclopropane ring bearing both cyano and carboxylic acid functionalities in trans configuration. This rigid, electron-deficient scaffold serves as a key building block for bioactive molecules and cyclic peptide mimetics. The compound exhibits enhanced stability under standard conditions and facilitates efficient derivatization via nucleophilic or coupling reactions.
trans-2-Cyanocyclopropane-1-carboxylic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of strained heterocyclic systems and functionalized cyclopropane scaffolds. Its bifunctional nature—combining a reactive nitrile group with a carboxylic acid—facilitates diverse transformations including nucleophilic additions, cyclizations, and derivatization under mild conditions. The trans configuration ensures defined stereochemistry, enhancing utility in stereoselective synthesis. Bench-stable and amenable to standard purification methods, it functions reliably in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: