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CS-W001157 4
Total: USD 88.00

6-Chloropyridine-2,3-dicarboxylic acid

  • CAS No. 127437-44-9

  • Cat. No. CS-0198357
  • Purity≥96%
  • MDL No.MFCD13689014

*For research and further manufacturing use only, not for direct human use.

6-Chloropyridine-2,3-dicarboxylic acid|CS-0198357

Structure of 127437-44-9

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General Information

  • CAS No. 127437-44-9
  • Cat. No. CS-0198357
  • Purity ≥96%
  • MDL No. MFCD13689014
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄ClNO₄
  • Molecular Weight 201.56
  • Synonym(s) 6-Chloropyridine-2,3-dicarboxylicacid
  • SMILES O=C(C1=NC(Cl)=CC=C1C(O)=O)O

Description

6-Chloropyridine-2,3-dicarboxylic acid features a chlorinated pyridine core flanked by two carboxylic acid groups, enabling robust coordination in metal-organic frameworks. This electron-deficient heterocycle integrates readily into chelating ligands and serves as a key building block for functionalized materials in catalysis and pharmaceutical synthesis.

Application

6-Chloropyridine-2,3-dicarboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling the construction of biologically relevant pyridine scaffolds. Its orthogonal functionalization profile—combining a reactive chlorine at C6 with two carboxylic acid groups—facilitates direct coupling, metal-catalyzed transformations, and derivatization under mild conditions. The compound exhibits excellent bench stability and ease of purification, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   87.49
  • LogP   1.1314
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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