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CS-W001157 4
Total: USD 88.00

2,6-Dibromopyridin-3-amine

  • CAS No. 39856-57-0

  • Cat. No. CS-W002394
  • Purity≥98%
  • MDL No.MFCD00128862

*For research and further manufacturing use only, not for direct human use.

2,6-Dibromopyridin-3-amine|CS-W002394

Structure of 39856-57-0

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General Information

  • CAS No. 39856-57-0
  • Cat. No. CS-W002394
  • Purity ≥98%
  • MDL No. MFCD00128862
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Br₂N₂
  • Molecular Weight 251.91
  • Synonym(s) 3-Amino-2,6-dibromopyridine
  • SMILES Brc1ccc(c(n1)Br)N

Description

3-Chlorophenol is widely used in the pharmaceutical, dyes and organic synthesis industry. It is an important intermediate in the synthesis of chemicals.

Application

2,6-Dibromopyridin-3-amine serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal bromine reactivity. The pyridine nitrogen enhances solubility and facilitates downstream functionalization, while the dibromo substitution pattern supports sequential derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in the synthesis of heterocyclic scaffolds and advanced intermediates for API development.

Synthesis

  • Route1
    • null|null
      462-08-8
    • ~92%
    • In-stock
      2,6-Dibromopyridin-3-amine|CS-W002394
      39856-57-0

    References

    • Majumdar; Mondal Tetrahedron Letters, 2007 , vol. 48, # 39 p. 6951 - 6953
  • Route2

    References

    • Kasparian, Annie J.; Savarin, Cecile; Allgeier, Alan M.; Walker, Shawn D. Journal of Organic Chemistry, 2011 , vol. 76, # 23 p. 9841 - 9844
  • Route3

    References

    • Canibano; Rodriguez; Santos; Sanz-Tejedor; Carreno; Gonzalez; Garcia-Ruano Synthesis, 2001 , # 14 p. 2175 - 2179

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H318
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.1888
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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