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CS-W001157 4
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Methyl 4-(hydroxymethyl)picolinate

  • CAS No. 317335-15-2

  • Cat. No. CS-W005573
  • Purity≥97%
  • MDL No.MFCD09834350

*For research and further manufacturing use only, not for direct human use.

Methyl 4-(hydroxymethyl)picolinate|CS-W005573

Structure of 317335-15-2

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General Information

  • CAS No. 317335-15-2
  • Cat. No. CS-W005573
  • Purity ≥97%
  • MDL No. MFCD09834350
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃
  • Molecular Weight None
  • Synonym(s) Methyl 4-(hydroxymethyl)pyridine-2-carboxylate
  • SMILES O=C(OC)C1=NC=CC(CO)=C1

Description

Methyl 4-(hydroxymethyl)picolinate features a pyridine ring bearing a methyl ester and hydroxymethyl group at the 4-position, enabling direct functionalization. This bench-stable derivative integrates readily into synthetic sequences requiring polar, electron-deficient heterocycles with orthogonal reactivity.

Application

Methyl 4-(hydroxymethyl)picolinate serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds. The hydroxymethyl group facilitates direct functionalization or oxidation to carboxylic acid, while the methyl ester supports selective transformations under standard conditions. Its bench-stable nature and compatibility with common coupling and protection strategies make it ideal for modular synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59.42
  • LogP   0.3605
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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