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Structure of 392-70-1
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4-Fluoro-2,6-dimethylaniline features a fluorine atom at the para position relative to the amino group, combined with methyl substituents at the ortho positions. This electron-deficient aromatic amine exhibits enhanced stability and selective reactivity in coupling processes. The steric hindrance from the adjacent methyl groups improves regioselectivity during electrophilic substitution, enabling precise functionalization in pharmaceutical intermediates and advanced materials synthesis.
4-Fluoro-2,6-dimethylaniline serves as a valuable building block in medicinal chemistry, offering a trifluorinated aromatic scaffold with enhanced metabolic stability. Its ortho-methyl groups provide steric shielding, improving bench stability and reducing unwanted side reactions. The molecule functions effectively in Suzuki-Miyaura couplings and amide formations, enabling efficient access to diverse heterocyclic frameworks and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: