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Structure of 392-13-2
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5-Fluoro-3-methyl-1H-indole is a fluorinated indole scaffold featuring a methyl group at the 3-position and a fluoro substituent at the 5-position. This electron-deficient heterocycle integrates readily into bioactive molecule design, offering enhanced metabolic stability and modulated electronic properties for medicinal chemistry applications.
5-Fluoro-3-methyl-1H-indole serves as a valuable building block in medicinal chemistry, enabling the synthesis of diverse heterocyclic scaffolds through standard electrophilic substitution and transition-metal-catalyzed coupling reactions. Its fluorinated indole core offers enhanced metabolic stability and modulated electronic properties, while the methyl group provides a site for further functionalization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthesis in API development and process chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H317
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: