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CS-W001157 4
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2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid

  • CAS No. 378247-75-7

  • Cat. No. CS-0182045
  • Purity≥95%
  • MDL No.MFCD13195295

*For research and further manufacturing use only, not for direct human use.

2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid|CS-0182045

Structure of 378247-75-7

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General Information

  • CAS No. 378247-75-7
  • Cat. No. CS-0182045
  • Purity ≥95%
  • MDL No. MFCD13195295
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₁₉NO₆
  • Molecular Weight None
  • Synonym(s) [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid
  • SMILES O=C(O)CC(C1=CC=C(NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)C=C1O5)=CC5=O

Description

This fluorenylmethoxycarbonyl-protected chromene derivative integrates a reactive acetic acid handle for peptide coupling, featuring enhanced solubility and stability under standard conditions. The electron-deficient chromenone core facilitates efficient conjugation in synthetic biology workflows.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • In-stock
      2-(7-Amino-2-oxo-2H-chromen-4-yl)acetic acid|CS-W005187
      85157-21-7
    • ~90%
    • In-stock
      2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)acetic acid|CS-0182045
      378247-75-7

    References

    • Maly, Dustin J.; Leonetti, Francesco; Backes, Bradley J.; Dauber, Deborah S.; Harris, Jennifer L.; Craik, Charles S.; Ellman, Jonathan A. Journal of Organic Chemistry, 2002 , vol. 67, # 3 p. 910 - 915

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   105.84
  • LogP   4.7811
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   5

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