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Structure of 392-04-1
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Methyl 4-fluoro-2-hydroxybenzoate features a strategically positioned fluorine atom and hydroxyl group on the aromatic ring, enabling enhanced electronic modulation and hydrogen-bonding capacity. This combination supports efficient integration into complex synthetic scaffolds, particularly in pharmaceutical intermediates requiring polar functionality and metabolic stability under standard conditions.
Methyl 4-fluoro-2-hydroxybenzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzene scaffolds. The ortho-hydroxyl group facilitates direct functionalization or coordination in transition metal-catalyzed processes, while the methyl ester supports standard hydrolysis, reduction, or coupling reactions. Bench-stable and amenable to purification by recrystallization, it functions reliably in multi-step syntheses requiring regioselective transformations.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: