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CS-W001157 4
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Amino-PEG6-alcohol

  • CAS No. 39160-70-8

  • Cat. No. CS-0108523
  • Purity≥95%
  • MDL No.MFCD22200781

*For research and further manufacturing use only, not for direct human use.

Amino-PEG6-alcohol|CS-0108523

Structure of 39160-70-8

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General Information

  • CAS No. 39160-70-8
  • Cat. No. CS-0108523
  • Purity ≥95%
  • MDL No. MFCD22200781
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₇NO₆
  • Molecular Weight 281.35
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCCOCCN

Description

Amino-PEG6-alcohol features a primary amine group flanked by a six-ethylene glycol unit and a terminal hydroxyl, offering enhanced solubility and controlled hydrophilicity. This structure enables conjugation via amine reactivity while maintaining stability under standard conditions.

Application

Amino-PEG6-alcohol serves as a versatile bifunctional linker in synthetic chemistry, enabling efficient conjugation of biomolecules and functionalization of surfaces. Its terminal amine and hydroxyl groups facilitate orthogonal reactions with carboxylic acids, activated esters, and epoxides, while the PEG6 spacer provides enhanced solubility and reduced non-specific binding. This compound demonstrates excellent bench stability, ease of purification, and compatibility with standard peptide and oligonucleotide synthesis protocols.

Synthesis

  • Route1

    References

    • Tamiaki, Hitoshi; Ogawa, Keishiro; Enomoto, Keisuke; Taki, Kazutaka; Hotta, Atsushi; Toma, Kazunori Tetrahedron, 2010 , vol. 66, # 9 p. 1661 - 1666
  • Route2

    References

    • Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503
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    • In-stock
      Amino-PEG6-alcohol|CS-0108523
      39160-70-8

    References

    • THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY; AUCKLAND UNISERVICES LIMITED; RUGA CORPORATION; GIACCA, Amato; LAI, Edwin; RAZORENOVA, Olga; CHAN, Denise; HAY, Michael, Patrick; BONNET, Muriel; SUN, Connie; TABIBIAZAR, Ray; YUEN, Po-wai Patent: WO2013/155338 A2, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   92.4
  • LogP   -0.9796
  • H_Acceptors   7
  • H_Donors   2
  • Rotatable_Bonds   16

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