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CS-W001157 4
Total: USD 88.00

NH2-PEG8-OH

  • CAS No. 352439-37-3

  • Cat. No. CS-0105698
  • Purity≥97%
  • MDL No.MFCD11041128

*For research and further manufacturing use only, not for direct human use.

NH2-PEG8-OH|CS-0105698

Structure of 352439-37-3

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General Information

  • CAS No. 352439-37-3
  • Cat. No. CS-0105698
  • Purity ≥97%
  • MDL No. MFCD11041128
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₅NO₈
  • Molecular Weight 369.45
  • Synonym(s) None
  • SMILES OCCOCCOCCOCCOCCOCCOCCOCCN

Description

NH2-PEG8-OH is a water-soluble, linear PEG derivative featuring a primary amine at one terminus and a hydroxyl group at the other. This dual-functional architecture enables site-specific conjugation and solubility enhancement in bioconjugation and drug delivery applications.

Application

NH₂-PEG₈-OH serves as a versatile bifunctional linker for conjugation and solubilization in synthetic chemistry. Its terminal amine enables coupling to carboxylic acid-containing molecules, while the hydroxyl group provides a handle for further derivatization or anchoring. The PEG8 spacer offers enhanced solubility and reduced aggregation, with demonstrated stability under standard bench conditions. Functions reliably in peptide modification, drug delivery systems, and polymer functionalization workflows.

Synthesis

  • Route1

    References

    • Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503
  • Route2
    • HO-PEG4-OH HQ|CS-1347183
      112-60-7
    • ~%
    • In-stock
      NH2-PEG8-OH|CS-0105698
      352439-37-3

    References

    • Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503
  • Route3

    References

    • Svedhem; Hollander; Shi; Konradsson; Liedberg; Svensson Journal of Organic Chemistry, 2001 , vol. 66, # 13 p. 4494 - 4503

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   110.86
  • LogP   -0.9464
  • H_Acceptors   9
  • H_Donors   2
  • Rotatable_Bonds   22

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