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Structure of 389843-61-2
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(R)-4-(tert-Butoxy)-2-isopropyl-4-oxobutanoic acid is a chiral β-keto ester derivative featuring a sterically hindered tert-butoxy group and a pendant isopropyl moiety. This configuration enhances stability and directs stereoselective transformations in asymmetric synthesis, particularly in the construction of complex carbocycles and heterocycles under mild conditions.
(R)-4-(tert-Butoxy)-2-isopropyl-4-oxobutanoic acid serves as a versatile chiral building block for the synthesis of bioactive heterocycles and functionalized carboxylic acid derivatives. Its α,β-unsaturated carbonyl motif enables reliable Michael additions and aldol-type condensations, while the tert-butoxy group provides excellent stability and orthogonal deprotection under mild acidic conditions. The isopropyl substituent enhances steric control in asymmetric transformations, making this compound well-suited for medicinal chemistry applications requiring stereochemical precision and facile downstream modification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P362-P405-P501
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Lot numbers can be found on the outside label of a product: