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Structure of 38876-70-9
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2-Bromo-6-hydroxybenzoic acid features a bromine atom at the ortho position relative to the carboxylic acid, combined with a para-hydroxyl group on the aromatic ring. This arrangement imparts enhanced polarity and reactivity, enabling efficient coupling in synthetic transformations. The molecule exhibits bench-stable behavior under standard conditions and integrates readily into complex molecular architectures requiring halogenated phenolic motifs.
2-Bromo-6-hydroxybenzoic acid serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the aromatic ring through palladium-catalyzed cross-coupling reactions. The carboxylic acid group facilitates derivatization via esterification or amide formation, while the phenolic hydroxyl and bromo substituents offer orthogonal reactivity for sequential modifications. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis of bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: