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CS-W001157 4
Total: USD 88.00

Triphenylphosphine sulfide

  • CAS No. 3878-45-3

  • Cat. No. CS-W012168
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Triphenylphosphine sulfide|CS-W012168

Structure of 3878-45-3

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General Information

  • CAS No. 3878-45-3
  • Cat. No. CS-W012168
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₁₅PS
  • Molecular Weight 294.35
  • Synonym(s) Triphenylphosphorus sulfide
  • SMILES S=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3

Description

Triphenylphosphine sulfide offers a robust, moisture-tolerant alternative to triphenylphosphine in transition metal-catalyzed cross-coupling reactions. This sulfur-modified phosphine features enhanced stability and improved solubility in polar aprotic solvents, enabling efficient ligand delivery under standard conditions.

Application

Triphenylphosphine sulfide serves as a stable, bench-ready alternative to triphenylphosphine in polar aprotic solvents, enabling efficient Wittig and Mitsunobu reactions with enhanced tolerance to moisture and air. Its robustness simplifies purification and improves reproducibility in synthetic workflows involving carbonyl olefination and stereoselective C–O bond formation.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.4424
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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