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Structure of 38749-90-5
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5-Bromo-2-ethylpyridine features a pyridine core bearing bromine at the 5-position and an ethyl group at the 2-position, creating a sterically accessible site for palladium-catalyzed cross-coupling reactions. The electron-deficient ring enhances reactivity in C–H functionalization, while the bench-stable nature allows handling under standard conditions. This dual-functionalized scaffold integrates readily into complex heterocyclic architectures.
5-Bromo-2-ethylpyridine serves as a versatile building block in medicinal chemistry and catalytic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined halogen functionality. The ethyl group at the 2-position provides steric and electronic modulation, enhancing regioselectivity in downstream transformations. Its bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for constructing complex heterocyclic scaffolds and API intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: